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KMID : 0361720130240030180
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Korean Journal of perinatology
2013 Volume.24 No. 3 p.180 ~ p.186
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Comparison of Obstetric and Neonatal Outcomes According to Oral Glucose Challenge Test in Korean Pregnant Women
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Yun Sung-Hyun
Han Sang-Won
Lee San-Hui
Jung Yong-Wook
Kim Eui-Hyeok
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Abstract
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Purpose: The purpose of the study was to compare obstetric and perinatal outcomes according to glucose challenge test (GCT) in a single institution.
Methods: One thousand six women, who were underwent antepartum gestational diabetes mellitus (GDM) screening by a GCT in mid-pregnancy and delivered at National Health Service between January 1, 2007 and July 31, 2012, were included in the study. The medical records of patients were analyzed retrospectively. The Subjects were categorized into three groups according to the results of 50 g oral GTC and 100 g oral GTC; normal glucose tolerance (NGT, n=826), less than 140 mg/dL; gestational impaired glucose tolerance (GIGT, n=128), more than 140 mg/dL but non-GDM ; gestational diabetes mellitus (GDM, n=52). Pre-existed maternal DM or hypertension and twin pregnancy were excluded. Obstetric
and perinatal outcomes were compared among the three groups.
Result: Maternal age, parity, and pre-pregnancy body mass index were higher in the GDM. The preterm delivery and gestational hypertension increased across the groups from NGT to GIGT to GDM (13.9% vs. 18.8% vs. 25.0%, P <0.01, and 1.9% vs.5.5% vs. 13.5%, P <0.01, respectively). Large for gestational age (LGA) and Neonatal Intensive Care Unit admission rate were higher in order in NGT, GIGT, and GDM (6.2% vs. 15.6% vs. 15.4%, P <0.01, and 12.3% vs. 24.2% vs. 38.5%, P <0.01), but other complications requiring intensive care were not different among the groups, including meconium aspiration syndrome and birth asphyxia.
Conclusion: GDM was a risk factor of cesarean section, preterm delivery, and gestational hypertension. In addition, GIGT was positively correlated with gestational hypertension, preterm labor, cesarean section rate, and LGA. This study suggests that there is a need to develop a guideline for Korean pregnant women who were diagnosed with GIGT.
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KEYWORD
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Gestational diabetes mellitus, Glucose challenge test, Pregnancy outcomes
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